When Ms. DiPesto has won a competition, she is allowed to join a Murder on the Orient Express (1974) inspired crime game in a train created by her favorite crime author. She is accompanied by Maddie and David to central station. Maddie and David miss to leave the train before it starts off and now have to stay on it since it won't stop for the next 48 hours. When a real murder happens, everybody is suspicious and the two detectives have to solve the crime.