In the 60´s, the Puerto Rican Carlito Brigante, the Afro-American Earl and the Italian Rocco become best friends while in prison. When they are released, Rocco intermediates a heroin business with a family of the Italian Mafia leaded by Artie Bottolota Sr. Carlito negotiates with the lord Leroy "Hollywood Nicky" Barnes the area where the trio could operate in his neighborhood and sooner the three friends become powerful. Later, Carlito dates and has an affair with the beautiful Leti